effect of eight weeks high intensity interval training on gene expression of pgc-1α, in male healthy rats fast-slow twitch muscles

the aim of the present study was to investigate the effect of hiit run on pgc-1α gene expression in fast & slow twitch muscles of healthy male  rats. for this purpose, 12 male wistar rats divided into two groups: contorol (n=6) and exercise (n=6) , respectively. intense interval training was consists of five days and a total of eight weeks,  that was formed the three frequencies ( 90 to 100% vo2max intensity for four minutes and two minutes at an intensity of 50 to 60% vo2max). 24 hours after the last training session, extensor digitorum longus muscle (edl) and soleus was extracted and relevant variables and expression levels were measured by rt-pcr. results showed a hiit run a significant increase pgc-1α gene expression in both muscle groups were trained (p=0/004 and p=0/001). according to the findings, implement hiit will be increases pgc-1α and oxidative capacity in sol and edl muscles.